CAS 186028-79-5 bkebdp mdmc white crystal research chemical for medical test
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Ethylone, or 3,4-methylenedioxy-N-ethylcathinone, is a synthetic molecule of the cathinone family. Cathinones are structurally similar to amphetamines in that they contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα.
contains an ethyl substitution at RN, a substitution which is shared with drugs like MDEA, 4-MEC, and certain other stimulants and entactogens.
ethylone contains substitutions at R3 and R4 of the phenyl ring with oxygen groups. These oxygen groups are incorporated into a methylenedioxy ring through a methylene chain. Ethylone shares this methylenedioxy ring with MDA, MDAI and MDME.
Ethylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine.These are the neurotransmitters in charge of pleasure, reward, motivation and focus.
This is done by inhibiting the reuptake and reabsorption of the neurotransmitters after they have performed their function of transmitting a neural impulse, essentially allowing them to accumulate and be reused, causing physically stimulating and euphoric effects.
In comparison to methylone, it has approximately over 3x lower affinity for the serotonin transporter (which itself has 3x lower affinity than ), while its affinity for the norepinephrine and dopamine transporters is similar.
The results of these differences in pharmacology relative to methylone is that ethylone is less potent in terms of dose, has more balanced catecholaminergic effects relative to serotonergic, and behaves more like a reuptake inhibitor like methylphenidate than a releaser like amphetamine; however, ethylone still has relatively robust releasing capabilities.
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